The Senior Biostatistician works independently in the production and quality control of analysis plans, reports, derived datasets, tables, listings, and figures in a clinical development setting. They provide statistical advice to clients and lead project teams to successful project completion within timelines and budget.

The Principal Biostatistician works independently on all level complexity clinical trial projects, often with major regulatory impact. Responsible for providing statistical support, leading production and quality control, performing sample-size calculations, and contributing to Data Monitoring Committee activities.